Pantostad 40 CAP

Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production.
  • Box of 28 capsules
  • 24 months
  • Pantoprazole
  • 40 mg
  • Hard gelatin capsule

Indications, Usage, Dosage and Administration


  • Treatment of gastro-oesophageal reflux disease (GORD).
  • Treatment of peptic ulcer disease.
  • Prophylasis for NSAID- associated ulceration.
  • Treatment of pathological hypersecretory states (Zollinger-Ellison syndrome).


  • Gastro-oesophageal reflux disease: 20 – 40 mg once daily for 4 to 8 weeks; thereafter, continued with 20 to 40 mg daily; for recurring symptoms, an on-demand of 20 mg daily may be given.
  • Peptic ulcer disease: 40 mg once daily for 2 – 4 weeks (duodenal ulcer) and 4 to 8 weeks (benign gastric ulcer). For the eradication of H. pylori, 1-week effective regimens: pantoprazole 40 mg twice daily + clarithromycin 500 mg twice daily + amoxicillin 1 g twice daily or metronidazole 400 mg twice daily.
  • Prophylaxis for NSAID- associated ulceration: 20 mg daily.
  • Zollinger-Ellison syndrome: commence with 80 mg once daily, adjusted as required; doses may be up to 240 mg daily. Daily doses greater than 80 mg should be given in 2 divided doses.
  • Hepatic impairment: Reduce daily doses in severe hepatic impairment, or doses given only on alternate days. A maximum dose of 20 mg daily, or 40 mg on alternate days.
  • Renal impairment: A maximum dose is 40 mg daily.


Pantostad 40 CAP is administered orally. Once daily doses should be taken in the morning.


Known hypersensitive to any of the active substance or excipients.

Adverse reactions

Diarrhea, hyperglycemia; headache, abdominal pain, abnormal liver function test results.


  • Symptomatic response to therapy with pantoprazole does not preclude the occult presence of gastric neoplasm.
  • Mild, transient elevations of serum ALT (SGPT) have been reported with oral pantoprazole therapy.
  • Pantoprazole may lead to malabsorption of cyanocobalamin.
  • Safety and efficacy in children younger than 18 years of age have not been established.
  • Pregnancy: There are no adequate studies. Lactation: a decision should be made whether to discontinue nursing or the drug.
  • Patients should be aware of how they react to drug before driving or operating machinery.
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